SCHEMBL187358

SCHEMBL187358

COC(=O)c1ccc(I)cc1S(=O)(=O)NC(=O)Nc1nc(C)nc(OC)n1.[NaH]

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.42
GAA P10253 1/20 0.39
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29508665 0.99 CDK1 (0.42) CDK1GAAALDH1A1KDM4ENPC1
SCHEMBL31392854 0.99 CDK1 (0.42) CDK1GAAALDH1A1KDM4ENPC1
SCHEMBL733383 0.99 CDK1 (0.42) CDK1GAAALDH1A1KDM4ENPC1
SCHEMBL31376086 0.98 CDK1 (0.42) CDK1GAAALDH1A1KDM4ENPC1
Iodosulfuron SCHEMBL6428400 0.96 CDK1 (0.40) CDK1GAAALDH1A1KDM4ENPC1
Iodosulfuron SCHEMBL6467038 0.95 CDK1 (0.40) CDK1GAAALDH1A1KDM4ENPC1
Iodosulfuron SCHEMBL6061256 0.92 CDK1 (0.42) CDK1GAAALDH1A1KDM4ENPC1
Iodosulfuron SCHEMBL21582014 0.92 CDK1 (0.42) CDK1GAAALDH1A1KDM4ENPC1
Iodosulfuron SCHEMBL119814 0.91 CDK1 (0.42) CDK1GAAALDH1A1KDM4ENPC1
Iodosulfuron SCHEMBL7638003 0.91 CDK1 (0.42) CDK1GAAALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2836072-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT Dongbu Farm Hannong Co., Ltd. (KR) 2015-02-18 EP claimed
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2015-01-22 US claimed
WO-2013154396-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2013-10-17 WO claimed
EP-2272361-B1 Herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)ones and iodosulfuron-methyl-sodium BAYER CROPSCIENCE AG (DE) 2012-08-22 EP claimed
US-7115543-B2 Aryl sulfonyl amino carbonyl triazole based selective herbicides BAYER CROPSCIENCE AG (DE) 2006-10-03 US claimed
US-20050192182-A1 Herbicidal mixtures based on substituted aryl ketones BAYER CROPSCIENCE AG (DE) 2005-09-01 US claimed
EP-1303189-B1 ARYL SULFONYL AMINO CARBONYL TRIAZOLE BASED SELECTIVE HERBICIDES BAYER CROPSCIENCE AG (DE) 2005-08-24 EP claimed
US-20050090397-A1 Herbicides made from substituted aryl ketones BAYER CROPSCIENCE AG (GB) 2005-04-28 US claimed
US-20050090396-A1 Herbicides based on substituted carboxylic acid anilides BAYER CROPSCIENCE AG (DE) 2005-04-28 US claimed
US-6849578-B1 Selective herbicides based on 2,6-disubstituted pyridine derivatives BAYER AKTIENGESELLSCHAFT (DE) 2005-02-01 US claimed
US-20050003963-A1 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-01-06 US claimed
US-20040171488-A1 N-aryl-uracils based Herbicides FEUCHT DIETER (DE) 2004-09-02 US claimed
CN-1509141-A Herbicides based on substituted aryl ketones �ݶ�ũ�����ѧ�ɷݹ�˾ 2004-06-30 CN claimed
US-20040116294-A1 Herbicides based on substituted aryl ketones BAYER CROPSCIENCE AG (DE) 2004-06-17 US claimed
US-6743754-B2 A SULFONYLUREA AND ONE OR MORE SURFACTANTS COMPRISING AS STRUCTURAL ELEMENT AT LEAST 10 ALKYLENE OXIDE UNITS. AVENTIS CROPSCIENCE GMBH (DE) 2004-06-01 US claimed
US-20030211942-A1 Aryl sulfonyl amino carbonyl triazole based selective herbicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-11-13 US claimed
CN-1449247-A Selective herbicides based on arylsulfonylaminocarbonyl triazolinones BAYER AG (DE) 2003-10-15 CN claimed
CN-118318843-A Application of methyl iodosulfuron sodium salt in controlling phytophthora diseases 沈阳农业大学 2024-07-12 CN disclosed
US-6569805-B1 Synergistic mixture of certain phenylsulfonylureas and/or their salts and vegetable oils for controlling weeds in crops AVENTIS CROPSCIENCE GMBH (DE) 2003-05-27 US disclosed
EP-1053679-A1 Herbicidal compositions AVENTIS CROPSCIENCE S.A. (FR) 2000-11-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050192182-A1 Herbicidal mixtures based on substituted aryl ketones DDT, CBR3, CYP1B1 CDK1 1685/4885GAA 690/4885ALDH1A1 148/4885
US-20030211942-A1 Aryl sulfonyl amino carbonyl triazole based selective herbicides AADAC, CBR3, ABAT CDK1 2425/4885GAA 576/4885ALDH1A1 591/4885
US-20050090396-A1 Herbicides based on substituted carboxylic acid anilides AADAC, NOTUM, NAAA CDK1 1989/4885GAA 326/4885ALDH1A1 95/4885
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT UNG, DDT, HDHD5 CDK1 1831/4885GAA 188/4885ALDH1A1 474/4885
US-20050090397-A1 Herbicides made from substituted aryl ketones DDT, CBR3, CBR1 CDK1 870/4885GAA 519/4885ALDH1A1 108/4885
US-20050003963-A1 Herbicides containing substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one DDT, TARS2, CBR3 CDK1 538/4885GAA 1644/4885ALDH1A1 284/4885
US-20040171488-A1 N-aryl-uracils based Herbicides DDT, UNG, DDC CDK1 1832/4885GAA 298/4885ALDH1A1 322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.