SCHEMBL1874083

SCHEMBL1874083

NC(=NC1CCCCC1)N(C1CCCCC1)N1CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.37
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2606340 0.74 ALOX5 (0.41)
SCHEMBL2606357 0.74 ALOX5 (0.41)
SCHEMBL3295724 0.74 SIGMAR1 (0.44) SIGMAR1KDM4E
SCHEMBL3295732 0.74 SIGMAR1 (0.44) SIGMAR1KDM4E
SCHEMBL3911153 0.71 SIGMAR1 (0.41) SIGMAR1KDM4E
SCHEMBL3921664 0.71 FAAH (0.42) SIGMAR1KDM4E
Bicarbonate SCHEMBL9555194 0.68 SIGMAR1 (0.39) SIGMAR1KDM4E
Bicarbonate SCHEMBL9555184 0.68 SIGMAR1 (0.39) SIGMAR1KDM4E
SCHEMBL3918313 0.67 SIGMAR1 (0.38) SIGMAR1KDM4E
SCHEMBL7758402 0.66 SIGMAR1 (0.37) SIGMAR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103025770-B Catalyst component for the polymerization of olefins having a guanidinate ligand DSM IP ASSETS BV 2015-06-24 CN disclosed
CN-103025770-A Catalyst component for the polymerization of olefins having a guanidinate ligand DSM IP ASSETS BV 2013-04-03 CN disclosed
EP-2496612-A1 CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS HAVING A GUANIDINATE LIGAND Lanxess Elastomers B.V. (NL) 2012-09-12 EP disclosed
WO-2011054927-A1 CATALYST COMPONENT FOR THE POLYMERIZATION OF OLEFINS HAVING A GUANIDINATE LIGAND DSM IP ASSETS B.V. (NL) 2011-05-12 WO disclosed