SCHEMBL18740940

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22443364	0.89	SHBG (0.39)	SHBGCYP19A1AKR1B10AKR1B1OR51E2
	SCHEMBL22443225	0.89	SHBG (0.39)	SHBGCYP19A1AKR1B10AKR1B1OR51E2
	SCHEMBL18741025	0.84	SHBG (0.38)	SHBGCYP19A1AKR1B10AKR1B1OR51E2
	SCHEMBL11456115	0.81	SHBG (0.42)	SHBGCYP19A1AKR1B10AKR1B1OR51E2
	SCHEMBL9314092	0.79	CYP19A1 (0.38)	SHBGCYP19A1AKR1B10AKR1B1OR51E2
	SCHEMBL9767861	0.77	SHBG (0.39)	SHBGCYP19A1AKR1B10AKR1B1OR51E2
	SCHEMBL22443205	0.73	SHBG (0.36)	SHBGCYP19A1AKR1B10AKR1B1OR51E2
	SCHEMBL14879774	0.72	ALDH1A1 (0.33)	SHBGCYP19A1CYP3A4MAPK1MAPT
	SCHEMBL14860281	0.72	CYP19A1 (0.35)	SHBGCYP19A1AKR1B10AKR1B1OR51E2
	SCHEMBL17988645	0.70	SHBG (0.38)	SHBGCYP19A1AKR1B10AKR1B1OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.