Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17195442 | 0.89 | KDM4E (0.48) | SMN1; SMN2ALOX15NFKB1BLMHPGD | |
| SCHEMBL13261240 | 0.84 | — | — | |
| SCHEMBL14337518 | 0.83 | BRD4 (0.31) | BRD4 | |
| SCHEMBL4676785 | 0.82 | — | — | |
| SCHEMBL22641025 | 0.82 | — | — | |
| SCHEMBL15003905 | 0.77 | HSD17B1 (0.30) | HSD17B1 | |
| SCHEMBL1075141 | 0.77 | AR (0.35) | THRBGAAMAPTLMNAKMT2A | |
| SCHEMBL20206904 | 0.75 | MMP1 (0.56) | — | |
| SCHEMBL13872418 | 0.75 | SMN1; SMN2 (0.61) | SMN1; SMN2ALOX15NFKB1BLMHPGD | |
| SCHEMBL16012524 | 0.73 | THRB (0.37) | SMN1; SMN2THRBMAPTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1247492-C | Cobalt catalyst composition for ethylene oligomerization and application thereof | CHINA NAT PETROLEUM CORP (CN) | 2006-03-29 | — | — | CN | claimed |
| CN-1166721-C | Method for preparing polyquinoxaline comprising pyrrole structural unit | 中国科学院长春应用化学研究所 | 2004-09-15 | — | — | CN | claimed |
| CN-1405207-A | Method for preparing polyquinoxaline comprising pyrrole structural unit | CHANGCHUN APPLIED CHEMISTRY (CN) | 2003-03-26 | — | — | CN | claimed |
| WO-2023079362-A1 | PROCESSABLE COMPOSITIONS AND USE FOR THE SAME | RIPPLE THERAPEUTICS CORPORATION (CA) | 2023-05-11 | — | — | WO | disclosed |
| US-9624520-B2 | Biosynthetically generated pyrroline-carboxy-lysine and site specific protein modifications via chemical derivatization of pyrroline-carboxy-lysine and pyrrolysine residues | NOVARTIS AG (CH) | 2017-04-18 | — | — | US | disclosed |
| CN-1166721-C | Method for preparing polyquinoxaline comprising pyrrole structural unit | 中国科学院长春应用化学研究所 | 2004-09-15 | — | — | CN | disclosed |
| CN-1405207-A | Method for preparing polyquinoxaline comprising pyrrole structural unit | CHANGCHUN APPLIED CHEMISTRY (CN) | 2003-03-26 | — | — | CN | disclosed |