Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142053 | 1.00 | SRC (0.46) | SRCTSHRSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL14247549 | 1.00 | SRC (0.46) | SRCTSHRSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL6648182 | 0.85 | MTNR1A (0.44) | SRCTSHRSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL5072835 | 0.85 | MTNR1A (0.44) | SRCTSHRSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL388144 | 0.85 | MTNR1A (0.44) | SRCTSHRSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL14588759 | 0.85 | TDP1 (0.47) | TSHRSMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL11720759 | 0.85 | CA1 (0.47) | TSHRSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL636993 | 0.84 | MAPT (0.46) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL13662396 | 0.84 | MAPT (0.46) | SMN1; SMN2NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL387761 | 0.84 | MTNR1A (0.43) | SRCTSHRSMN1; SMN2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036790-A | Chiral phosphine-acyclic phosphoramidite ligand, preparation method and application thereof | 中国科学院大连化学物理研究所 | 2026-05-15 | — | — | CN | disclosed |
| CN-113121615-B | Ferrocene boracic chiral diphosphine ligand and preparation method and application thereof | 南方科技大学 | 2023-02-17 | — | — | CN | disclosed |
| CN-112824422-B | Chiral ferrocene-indole diphosphine ligand as well as preparation method and application thereof | 中国科学院大连化学物理研究所（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-113121615-A | Ferrocene boracic chiral diphosphine ligand and preparation method and application thereof | 南方科技大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-112824423-A | Chiral ferrocenylphosphine-indolylaminophosphine ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2021-05-21 | — | — | CN | disclosed |
| EP-3768688-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | Université de Bourgogne (FR) | 2021-01-27 | — | — | EP | disclosed |
| US-20200407381-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | Université de Bourgogne (FR) | 2020-12-31 | — | — | US | disclosed |
| CN-111868065-A | C-sterically hindered P-chirally derived organophosphorus compounds | 勃艮第大学 | 2020-10-30 | — | — | CN | disclosed |
| WO-2019180084-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | Université de Bourgogne (FR) | 2019-09-26 | — | — | WO | disclosed |
| CN-108339571-A | P- chiral source organic phosphorus compounds | 国家科学研究中心 | 2018-07-31 | — | — | CN | disclosed |
| US-20020042540-A1 | New 6,6'-bis-(1-phosphanorbornadiene) diphosphines, their preparation and their uses | MATHEY FRANCOIS (FR) | 2002-04-11 | — | — | US | disclosed |
| WO-2002002578-A1 | FERROCENYL DIPHOSPHINES AND THEIR USE | SOLVIAS AG (CH) | 2002-01-10 | — | — | WO | disclosed |
| US-6288279-B1 | THEIR PREPARATION PROCESS AND THEIR USE IN ASYMMETRICAL CATALYSIS. REARRANGING A DIPHOSPHOLE, REACTING THE DIPHOSPHOLE WITH AN ACETYLENIC COMPOUND TO FORM THE DIPHOSPHINE | RHODIA CHIMIE (FR) | 2001-09-11 | — | — | US | disclosed |
| US-6037493-A | Optically active diphosphines, preparation thereof according to a process for the resolution of the racemic mixture and use thereof | RHONE-POULENC CHIMIE (FR) | 2000-03-14 | — | — | US | disclosed |
| WO-1999059721-A1 | CATALYTIC ASYMMETRIC HYDROGENATION, HYDROFORMYLATION, AND HYDROVINYLATION VIA TRANSITION METAL CATALYSTS WITH PHOSPHINES AND PHOSPHITES | THE PENN STATE RESEARCH FOUNDATION (US) | 1999-11-25 | — | — | WO | disclosed |
| US-5783738-A | Optically active diphosphines, preparation thereof according to a process for the resolution of the racemic mixture and use thereof | RHONE-POULENC CHIMIE (FR) | 1998-07-21 | — | — | US | disclosed |
| EP-0198397-B1 | METHOD OF PRODUCING L-PHENYLALANINE | KURARAY CO., LTD. (JP) | 1993-01-07 | — | — | EP | disclosed |
| US-4743547-A | PURITY, ENZYME HYDROLYSIS | KURARAY CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| US-4654176-A | Sulphonated chiral phosphines, their preparation and their use | RHONE-POULENC SANTE (FR) | 1987-03-31 | — | — | US | disclosed |
| EP-0198397-A2 | Method of producing L-phenylalanine | KURARAY CO., LTD. (JP) | 1986-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407381-A1 | C-BULKY P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS | PLCG1, PLCG2, ACHE | SRC 1837/4885TSHR 3498/4885SMN1; SMN2 2652/4885 |
| US-20020042540-A1 | New 6,6'-bis-(1-phosphanorbornadiene) diphosphines, their preparation and their uses | PHOSPHO1, DUS2, DCPS | SRC 3914/4885TSHR 4146/4885SMN1; SMN2 3776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.