SCHEMBL18748136

SCHEMBL18748136

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)nc(-c3ccccc3)c3ccc5ccc6ncccc6c5c34)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43
WHR1 P49842 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP1A1 P04798 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP1B1 Q16678 1/20 0.38
LMNA P02545 2/20 0.36
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
MAPT P10636 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
RECQL P46063 1/20 0.36
KDM4E B2RXH2 2/20 0.36
MAPK10 P53779 1/20 0.35
PIK3CA P42336 2/20 0.35
PIK3CD O00329 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18748089 0.94 MEN1 (0.49) MEN1KMT2AATMCYP3A4CYP1A1
SCHEMBL18748132 0.93 CYP3A4 (0.38) MEN1KMT2AATMWHR1CYP3A4
SCHEMBL18748106 0.90 CYP3A4 (0.40) MEN1KMT2AATMWHR1CYP3A4
SCHEMBL18748124 0.87 WHR1 (0.40) MEN1KMT2AATMWHR1CYP3A4
SCHEMBL24609823 0.84 CYP3A4 (0.41) MEN1KMT2AATMWHR1CYP3A4
SCHEMBL17997935 0.84 WHR1 (0.41) MEN1KMT2AATMWHR1CYP3A4
SCHEMBL18748134 0.84 PIK3CA (0.44) ATMCYP3A4CYP1A2LMNACSNK2A2
SCHEMBL19051795 0.82 MEN1 (0.42) MEN1KMT2AATMWHR1CSNK2A2
SCHEMBL18748145 0.82 LMNA (0.43) MEN1KMT2ACYP3A4CYP1A1CYP1A2
SCHEMBL17035030 0.82 MEN1 (0.49) MEN1KMT2AATMWHR1CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10319919-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-06-11 US disclosed
US-20170110671-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-20 US disclosed
US-20170110671-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10319919-B2 Compound and organic light-emitting device including the same LOXL1, ELOVL1, LPO MEN1 702/4885KMT2A 1532/4885ATM 4019/4885
US-20170110671-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME LOXL1, ELOVL1, LPO MEN1 702/4885KMT2A 1532/4885ATM 4019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.