Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | CCR8 | P51685 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997893 | 0.96 | LMNA (0.35) | LMNATOP2ATOP1KDM4EMAPT | |
| SCHEMBL17035059 | 0.90 | LMNA (0.35) | LMNATOP2ATOP1KDM4EMAPT | |
| SCHEMBL19051813 | 0.89 | TOP2A (0.35) | TOP2ATOP1KDM4EMAPTMEN1 | |
| SCHEMBL17997923 | 0.88 | TOP2A (0.39) | LMNATOP2ATOP1KDM4EMAPT | |
| SCHEMBL18748154 | 0.88 | TOP1 (0.38) | LMNATOP1KDM4EMAPTNPC1 | |
| SCHEMBL17035050 | 0.87 | BRD4 (0.39) | LMNATOP2ATOP1KDM4EMAPT | |
| SCHEMBL17035051 | 0.87 | KDM4E (0.36) | LMNATOP2ATOP1KDM4EMAPT | |
| SCHEMBL19051816 | 0.87 | TOP2A (0.36) | TOP2ATOP1KDM4EMAPTMEN1 | |
| SCHEMBL17035032 | 0.86 | ESR1 (0.38) | LMNAKDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL18748142 | 0.85 | LMNA (0.38) | LMNATOP1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10319919-B2 | Compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-06-11 | — | — | US | disclosed |
| US-20170110671-A1 | COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-04-20 | — | — | US | disclosed |
| US-20170110671-A1 | COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10319919-B2 | Compound and organic light-emitting device including the same | LOXL1, ELOVL1, LPO | LMNA 1653/4885TOP2A 3680/4885TOP1 1319/4885 |
| US-20170110671-A1 | COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | LOXL1, ELOVL1, LPO | LMNA 1653/4885TOP2A 3680/4885TOP1 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.