Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1875226 | 1.00 | SLC22A12 (0.46) | SLC22A12ALDH1A1KDM4EHSD17B10CYP3A4 | |
| SCHEMBL1610377 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4ECYP3A4HPGDMAPK1 | |
| SCHEMBL12658705 | 0.81 | ITGB2 (0.45) | ALDH1A1KDM4EHSD17B10CYP3A4HPGD | |
| SCHEMBL1609782 | 0.80 | POLB (0.38) | ALDH1A1KDM4ECYP3A4CYP2C9POLB | |
| SCHEMBL1609779 | 0.80 | POLB (0.38) | ALDH1A1KDM4ECYP3A4CYP2C9POLB | |
| SCHEMBL12536230 | 0.79 | KDM4E (0.40) | ALDH1A1KDM4ECYP3A4CYP2C9SMN1; SMN2 | |
| SCHEMBL14321468 | 0.79 | KDM4E (0.40) | ALDH1A1KDM4ECYP3A4CYP2C9TSHR | |
| SCHEMBL12658707 | 0.75 | S1PR3 (0.42) | ALDH1A1S1PR3 | |
| SCHEMBL5216721 | 0.74 | SMN1; SMN2 (0.63) | ALDH1A1KDM4ECYP3A4MAPK1MEN1 | |
| SCHEMBL5475832 | 0.74 | S1PR3 (0.45) | ALDH1A1KDM4EMEN1KMT2AS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889878-B2 | Haloalky-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-11-18 | — | — | US | disclosed |
| US-8710242-B2 | Haloalky -substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2014-04-29 | — | — | US | disclosed |
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-04 | — | — | US | disclosed |
| US-20110105532-A1 | Haloalkyl-substituted amides as insecticides and acaricides | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172390-A1 | Haloalkyl-Substituted Amides as Insecticides and Acaricides | CRYAA, ACLY, CRYZ | SLC22A12 3031/4885ALDH1A1 769/4885KDM4E 1789/4885 |
| US-20110105532-A1 | Haloalkyl-substituted amides as insecticides and acaricides | CRYAA, ACLY, CRYZ | SLC22A12 3031/4885ALDH1A1 769/4885KDM4E 1789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.