Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 10/20 | 0.50 |
| ▸ | YAP1 | P46937 | 1/20 | 0.48 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.48 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18752850 | 0.95 | RXFP1 (0.45) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL12801457 | 0.89 | LMNA (0.54) | RXFP1TEAD4MAPTPOLBLMNA | |
| SCHEMBL18752846 | 0.84 | LMNA (0.51) | RXFP1TEAD4MAPTPOLBLMNA | |
| SCHEMBL12801807 | 0.80 | MT-CO2 (0.48) | MAPTLMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18752851 | 0.77 | RXFP1 (0.54) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL12606017 | 0.76 | RXFP1 (0.67) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL16386151 | 0.75 | MT-CO2 (0.43) | MAPTLMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13929951 | 0.74 | RXFP1 (0.64) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL1774875 | 0.74 | RXFP1 (0.70) | RXFP1YAP1TEAD4TEAD2TRPV1 | |
| SCHEMBL18286751 | 0.72 | RXFP1 (0.53) | RXFP1YAP1TEAD4TEAD2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092806-A1 | Compounds Comprising a Biological Target Recognizing Part, Coupled to a Signal Part Capable of Complexing Gallium | GUEREBET (FR) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092806-A1 | Compounds Comprising a Biological Target Recognizing Part, Coupled to a Signal Part Capable of Complexing Gallium | KLK3, IGF1R, GIPR | RXFP1 634/4885YAP1 1314/4885TEAD4 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.