Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18754199 | 0.83 | AR (0.40) | — | |
| SCHEMBL18754141 | 0.78 | CA2 (0.33) | — | |
| SCHEMBL18754179 | 0.76 | KCNH2 (0.37) | — | |
| SCHEMBL20244887 | 0.75 | MAOB (0.45) | — | |
| SCHEMBL16114778 | 0.74 | ALDH1A1 (0.45) | MCHR1BRD4CCL2 | |
| SCHEMBL24456046 | 0.69 | HTT (0.34) | — | |
| SCHEMBL27872308 | 0.69 | CA2 (0.55) | — | |
| SCHEMBL24785850 | 0.68 | LMNA (0.41) | — | |
| SCHEMBL19230507 | 0.68 | MAPT (0.33) | — | |
| SCHEMBL5949918 | 0.67 | NQO1 (0.43) | BRD4CCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978754-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-10 | — | — | EP | disclosed |
| EP-2978747-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-04-19 | — | — | EP | disclosed |