Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12288420 | 0.79 | SMN1; SMN2 (0.59) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL12902980 | 0.75 | HTR2A (0.55) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL3385311 | 0.73 | HDAC1 (0.47) | MEN1KMT2AALOX15LMNAMAPK1 | |
| SCHEMBL10603693 | 0.73 | APP (0.67) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL3028100 | 0.73 | APP (0.67) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL24891034 | 0.73 | APP (0.67) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL1120950 | 0.72 | CES2 (0.41) | MEN1KMT2AMAPK1APPCYP3A4 | |
| SCHEMBL4886159 | 0.72 | KMT2A (0.44) | MAPTMEN1KMT2ASMN1; SMN2ALOX15 | |
| SCHEMBL8119143 | 0.72 | ALDH1A1 (0.50) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL13978791 | 0.71 | ALDH1A1 (0.50) | MAPTMEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2727912-B1 | CRYSTALS OF GLYCINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | TORAY INDUSTRIES (JP) | 2017-04-19 | — | — | EP | disclosed |