SCHEMBL4886159

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29912449	0.80	CYP2D6 (0.44)	KMT2ACES1APPGRM1CYP2D6
	SCHEMBL13338158	0.80	CYP2D6 (0.44)	KMT2ACES1APPGRM1CYP2D6
	SCHEMBL2567211	0.80	PTGS1 (0.39)	CES1APPPTGS1PTGS2HDAC1
	SCHEMBL3385311	0.79	HDAC1 (0.47)	KMT2AHDAC1HDAC6CYP1A2CYP3A4
	SCHEMBL8119143	0.78	ALDH1A1 (0.50)	KMT2ACYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL1120950	0.78	CES2 (0.41)	KMT2ACES1APPHDAC1HDAC6
	SCHEMBL13338132	0.78	APP (0.52)	KMT2ACES1APPCYP1A2MAPK1
	SCHEMBL2567160	0.76	ALDH1A1 (0.43)	KMT2ACES1APPPTGS1PTGS2
	SCHEMBL2566482	0.76	ALDH1A1 (0.38)	KMT2AAPPPTGS1PTGS2HDAC1
	SCHEMBL5998627	0.76	CHRM5 (0.52)	KMT2ACES1APPGRM1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.