Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19302972 | 0.83 | ALDH1A1 (0.69) | PKMNAMPTALDH1A1CYP2C19MAPT | |
| SCHEMBL10131252 | 0.82 | LMNA (0.60) | PKMNAMPTMEN1KMT2ALMNA | |
| SCHEMBL13592382 | 0.81 | MAPT (0.68) | PKMMEN1KMT2APTPN1PTPN2 | |
| SCHEMBL17224981 | 0.81 | PTPN1 (0.65) | NAMPTMEN1KMT2ALMNAPTPN1 | |
| SCHEMBL1553445 | 0.79 | ROCK2 (0.62) | PKMNAMPTKMT2ALMNACARM1 | |
| SCHEMBL19173420 | 0.79 | SIRT2 (0.53) | NAMPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL1353592 | 0.79 | PKM (0.55) | PKMNAMPTLMNAALDH1A1CYP2C19 | |
| SCHEMBL23291304 | 0.77 | MEN1 (0.51) | PKMNAMPTMEN1KMT2ALMNA | |
| SCHEMBL21994191 | 0.77 | EPHX2 (0.60) | PKMMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL23928217 | 0.76 | POLB (0.55) | PKMNAMPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268375-B1 | PHOTOCHROMIC THIENOCHROMENE COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-2651913-B1 | INDENO-FUSED RING COMPOUNDS HAVING PHOTOCHROMIC PROPERTIES | TRANSITIONS OPTICAL INC (US) | 2017-04-19 | — | — | EP | disclosed |