Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1877301 | 0.91 | GHSR (0.37) | QPCTCCR2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL1876380 | 0.91 | QPCT (0.34) | PPARAPPARGQPCTKCNH2PPARD | |
| Trifluoroacetic Acid SCHEMBL1878705 | 0.89 | CCR2 (0.37) | BTKCCR2 | |
| Trifluoroacetic Acid SCHEMBL1874258 | 0.86 | BTK (0.37) | PPARAPPARGBTK | |
| SCHEMBL12634101 | 0.86 | QPCT (0.45) | QPCTKCNH2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL1874615 | 0.86 | SLC2A1 (0.38) | QPCTFFAR1 | |
| Trifluoroacetic Acid SCHEMBL1875567 | 0.86 | SLC2A1 (0.38) | QPCTFFAR1 | |
| Trifluoroacetic Acid SCHEMBL4639063 | 0.85 | IL6 (0.35) | QPCTCCR2 | |
| Trifluoroacetic Acid SCHEMBL1878480 | 0.85 | IL6 (0.35) | QPCTCCR2 | |
| Trifluoroacetic Acid SCHEMBL1873575 | 0.84 | PTK2 (0.35) | QPCTCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939528-B2 | Heterocycle compounds | GLAXOSMITHKLINE LLC (US) | 2011-05-10 | — | — | US | disclosed |