Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276792 | 0.82 | TDP1 (0.49) | SMN1; SMN2GAAMEN1KMT2ACA12 | |
| SCHEMBL1276827 | 0.80 | TDP1 (0.54) | SMN1; SMN2GAAMEN1KMT2ACA12 | |
| SCHEMBL2744213 | 0.79 | APLNR (0.49) | SMN1; SMN2APLNRGAAMEN1KMT2A | |
| SCHEMBL5136229 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2GAAMEN1KMT2ACA12 | |
| SCHEMBL4756453 | 0.78 | APLNR (0.51) | SMN1; SMN2APLNRGAAMEN1KMT2A | |
| SCHEMBL23629625 | 0.77 | NAMPT (0.50) | SMN1; SMN2MEN1KMT2AMAPK1CA12 | |
| SCHEMBL25657888 | 0.77 | ADRB2 (0.44) | SMN1; SMN2GAAMEN1KMT2ACA12 | |
| SCHEMBL29720151 | 0.77 | TDP1 (0.48) | SMN1; SMN2GAAMEN1KMT2ACA12 | |
| SCHEMBL284141 | 0.77 | APLNR (0.55) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL10360743 | 0.76 | MEN1 (0.40) | SMN1; SMN2MEN1KMT2AMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414473-B | Polyene macrolide derivatives | 盐野义制药株式会社 | 2020-03-13 | — | — | CN | disclosed |
| EP-3156410-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-04-19 | — | — | EP | disclosed |