Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19091349 | 0.84 | MEN1 (0.46) | MEN1MAPK1KMT2AGAAAPLNR | |
| SCHEMBL18756246 | 0.80 | MEN1 (0.45) | MEN1MAPK1KMT2AGAAAPLNR | |
| SCHEMBL284141 | 0.71 | APLNR (0.55) | MEN1MAPK1KMT2AGAAAPLNR | |
| SCHEMBL2391753 | 0.68 | MEN1 (0.44) | MEN1MAPK1KMT2AGAAAPLNR | |
| SCHEMBL31021338 | 0.68 | BTK (0.45) | MEN1MAPK1KMT2AGAAAPLNR | |
| SCHEMBL19091087 | 0.67 | GAA (0.43) | MEN1MAPK1KMT2AGAAAPLNR | |
| SCHEMBL17191703 | 0.67 | MEN1 (0.43) | MEN1MAPK1KMT2AGAACHRM2 | |
| SCHEMBL11525177 | 0.67 | MEN1 (0.56) | MEN1MAPK1KMT2AGAAAPLNR | |
| SCHEMBL18756648 | 0.66 | DGAT1 (0.38) | MEN1KMT2A | |
| SCHEMBL23038833 | 0.66 | MEN1 (0.45) | MEN1MAPK1KMT2AGAAAPLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156410-A1 | POLYENE MACROLIDE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2017-04-19 | — | — | EP | disclosed |