Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24114400 | 0.88 | CTSS (0.51) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL18759664 | 0.85 | CCKBR (0.45) | CTSSCTSKACECCKBRSYK | |
| SCHEMBL24465207 | 0.85 | CCKBR (0.45) | CTSSCTSKACECCKBRSYK | |
| SCHEMBL18759227 | 0.85 | CHRNB2 (0.48) | CTSSCTSKACECTSBCTSL | |
| SCHEMBL24465200 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2 | |
| SCHEMBL24130775 | 0.79 | KLK5 (0.53) | CTSSCTSKACESYKCTSB | |
| SCHEMBL24130777 | 0.79 | KLK5 (0.53) | CTSSCTSKACESYKCTSB | |
| SCHEMBL18759283 | 0.78 | CTSS (0.48) | CTSSCTSKACE | |
| SCHEMBL24130736 | 0.75 | ACE (0.56) | CTSSCTSKACECCKBRREN | |
| SCHEMBL24130739 | 0.75 | ACE (0.56) | CTSSCTSKACECCKBRREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066763-A1 | PROTEASOME INHIBITORS AND USES THEREOF | CORNELL UNIVERSITY (US) | 2017-04-20 | — | — | WO | disclosed |