SCHEMBL18760656

SCHEMBL18760656

Cc1cc2c(oc3ccccc32)c(C)c1C

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.49
MAOA P21397 4/20 0.44
TTR P02766 1/20 0.42
KDM4E B2RXH2 5/20 0.41
CYP1A2 P05177 1/20 0.41
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CYP3A4 P08684 1/20 0.40
PKM P14618 1/20 0.40
RECQL P46063 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ALOX5 P09917 2/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10227386 0.86 AHR (0.53) AHRMAOATTRKDM4ECYP1A2
SCHEMBL14295772 0.82 AHR (0.50) AHRMAOATTRKDM4ECYP1A2
SCHEMBL24449222 0.81 AHR (0.42) AHRMAOATTRKDM4ECYP1A2
SCHEMBL22185971 0.80 AHR (0.41) AHRMAOATTRKDM4ECYP1A2
SCHEMBL12811238 0.79 AHR (0.47) AHRMAOATTRKDM4ECYP1A2
SCHEMBL16283915 0.79 AHR (0.47) AHRMAOAKDM4ECYP1A2MEN1
SCHEMBL25517145 0.79 MAOB (0.41) AHRKDM4ECYP1A2MEN1KMT2A
SCHEMBL25517167 0.79 MAPT (0.41) AHRKDM4EMEN1KMT2AALDH1A1
SCHEMBL11976508 0.79 MAOB (0.35) AHRMAOAKDM4ECYP1A2ALDH1A1
SCHEMBL13021646 0.78 PGR (0.45) AHRMAOAKDM4ECYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295449-A1 COMPOSITION AND LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-09-21 US disclosed
US-11021568-B2 Polymer compound and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-01 US disclosed
US-20210087330-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-03-25 US disclosed
US-10290818-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-05-14 US disclosed
US-20170110673-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10290818-B2 Organometallic compound and organic light-emitting device including the same L1CAM, L3MBTL1, LEF1 AHR 1313/4885MAOA 3008/4885TTR 1819/4885
US-20170110673-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME L1CAM, L3MBTL1, LEF1 AHR 1313/4885MAOA 3008/4885TTR 1819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.