Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25C | P30307 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25517153 | 0.86 | ADORA3 (0.43) | MAOBHPGDALDH1A1ADORA3AHR | |
| SCHEMBL25517167 | 0.85 | MAPT (0.41) | HPGDALDH1A1ADORA3AHRMAPT | |
| SCHEMBL11976514 | 0.83 | MCL1 (0.43) | MAOBHPGDALDH1A1GAACDC25A | |
| SCHEMBL25517172 | 0.82 | CA12 (0.42) | MAOBHPGDALDH1A1ADORA3MAPT | |
| SCHEMBL26749899 | 0.80 | NQO1 (0.37) | MAOBHPGDALDH1A1ADORA3AHR | |
| SCHEMBL13563983 | 0.80 | MAOB (0.48) | MAOBHPGDALDH1A1GAACDC25A | |
| SCHEMBL26293026 | 0.79 | CSNK2A2 (0.46) | MAOBHPGDALDH1A1GAACDC25A | |
| SCHEMBL18760656 | 0.79 | AHR (0.49) | HPGDALDH1A1AHRMAPTSMN1; SMN2 | |
| SCHEMBL18327972 | 0.79 | DYRK1A (0.49) | MAOBHPGDALDH1A1GAACDC25A | |
| SCHEMBL10031365 | 0.78 | MAOB (0.50) | MAOBHPGDALDH1A1GAACDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230320191-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| US-11659763-B2 | Metal complexes | MERCK PATENT GMBH | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230320191-A1 | METAL COMPLEXES | IMMT, MCU, SOD1 | MAOB 2037/4885HPGD 3769/4885ALDH1A1 1473/4885 |
| US-11659763-B2 | Metal complexes | IMMT, MCU, SOD1 | MAOB 2037/4885HPGD 3769/4885ALDH1A1 1473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.