Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.35 |
| ▸ | CPB1 | P15086 | 3/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4900683 | 0.70 | CPB2 (0.34) | CPB2CPB1 | |
| SCHEMBL21404585 | 0.67 | CPB2 (0.34) | CPB2CPB1 | |
| SCHEMBL16828766 | 0.67 | ALDH1A1 (0.42) | — | |
| SCHEMBL16853579 | 0.65 | KDM4E (0.39) | — | |
| SCHEMBL19859584 | 0.65 | CPB2 (0.43) | CPB2CPB1 | |
| SCHEMBL11908082 | 0.65 | KDM5A (0.37) | CPB2CPB1 | |
| SCHEMBL584619 | 0.63 | CA12 (0.41) | — | |
| SCHEMBL25416452 | 0.62 | — | — | |
| SCHEMBL2533783 | 0.62 | PKM (0.34) | — | |
| SCHEMBL23320277 | 0.62 | TBXAS1 (0.42) | CPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496557-A1 | TETRAHYDROQUINOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | GlaxoSmithKline LLC (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011054841-A1 | TETRAHYDROQUINOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | GLAXOSMITHKLINE LLC (US) | 2011-05-12 | — | — | WO | disclosed |