Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615865 | 0.89 | SRD5A2 (0.55) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL9066312 | 0.87 | ALDH1A1 (0.93) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL314267 | 0.87 | ALDH1A1 (0.93) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL3709049 | 0.85 | CES2 (0.75) | ALDH1A1SRD5A2L3MBTL1ATMRAB9A | |
| Benzophenone SCHEMBL5032137 | 0.84 | ALDH1A1 (0.88) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| Benzophenone SCHEMBL3677415 | 0.84 | ALDH1A1 (0.88) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| Benzophenone SCHEMBL30536983 | 0.84 | ALDH1A1 (1.00) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| Benzophenone SCHEMBL30537001 | 0.84 | ALDH1A1 (1.00) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| Benzophenone SCHEMBL28491203 | 0.84 | ALDH1A1 (1.00) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| Benzophenone SCHEMBL6061130 | 0.84 | ALDH1A1 (1.00) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114981280-A | Method for producing oligonucleotide compound | 日本新药株式会社 | 2022-08-30 | — | — | CN | claimed |
| CN-105473591-B | EphA4 inhibitors as neuroprotective agents | 香港科技大学 | 2018-02-23 | — | — | CN | claimed |
| EP-3022206-A1 | EphA4 INHIBITORS AS NEUROPROTECTIVE AGENTS | The Hong Kong University of Science and Technology (CN) | 2016-05-25 | — | — | EP | claimed |
| EP-2850111-A1 | NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS | Coloplast A/S (DK) | 2015-03-25 | — | — | EP | claimed |
| WO-2015007222-A1 | EphA4 INHIBITORS AS NEUROPROTECTIVE AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-01-22 | — | — | WO | claimed |
| CN-104185661-A | Lubricious medical device coating with low particulates | SURMODICS INC | 2014-12-03 | — | — | CN | claimed |
| US-8669253-B2 | Methods for treating glaucoma and macular degeneration | DUKE UNIVERSITY (US) | 2014-03-11 | — | — | US | claimed |
| WO-2013170858-A1 | NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS | COLOPLAST A/S (DK) | 2013-11-21 | — | — | WO | claimed |
| US-8466295-B2 | Thiophene derivatives as factor XIa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-06-18 | — | — | US | claimed |
| US-20120270853-A1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-10-25 | — | — | US | claimed |
| EP-0649431-A4 | 17-AMINO SUBSTITUTED 4-AZASTEROID 5-G(A)-REDUCTASE INHIBITORS. | — | 1995-05-03 | — | — | EP | claimed |
| EP-0649431-A1 | 17-AMINO SUBSTITUTED 4-AZASTEROID 5$g(a)-REDUCTASE INHIBITORS | MERCK & CO. INC. (US) | 1995-04-26 | — | — | EP | claimed |
| EP-0641208-A1 | 4-AZASTEROID 5-ALPHA-REDUCTASE INHIBITORS | MERCK & CO. INC. (US) | 1995-03-08 | — | — | EP | claimed |
| CN-1087092-A | Novel 7 beta-substituted-4-aza-5 alpha-androstan-3-ones as 5 alpha-reductase inhibitors | MERCK & CO INC (US) | 1994-05-25 | — | — | CN | claimed |
| EP-0572166-A1 | New 7beta-substituted-4-aza-5a-androstan-3-ones as 5a-reductase inhibitors | MERCK & CO. INC. (US) | 1993-12-01 | — | — | EP | claimed |
| WO-1993023038-A1 | 17-AMINO SUBSTITUTED 4-AZASTEROID 5α-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |
| WO-1993023039-A1 | SUBSTITUTED 4-AZA-5A-ANDROSTAN-ONES AS 5A-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |
| WO-1993023420-A1 | NEW 7β-SUBSTITUTED-4-AZA-5α-ANDROSTAN-3-ONES AS 5α-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |
| WO-1993023048-A1 | 4-AZASTEROID 5-ALPHA-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |
| US-4181733-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1980-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270853-A1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | TFPI, F11, F12 | ALDH1A1 1874/4885SRD5A2 3840/4885L3MBTL1 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.