Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 3/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30143246 | 0.86 | S1PR1 (0.38) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL18763972 | 0.86 | S1PR1 (0.38) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL17293172 | 0.85 | HTR1A (0.41) | ALDH1A1RXRARXRBRXRGCYP3A4 | |
| SCHEMBL9873789 | 0.79 | MAPT (0.39) | NPC1ALDH1A1RAB9AKDM4EMAPT | |
| SCHEMBL18774721 | 0.79 | HTR1A (0.37) | ALDH1A1L3MBTL1KDM4EMAPTCYP1A2 | |
| SCHEMBL27677983 | 0.76 | CYP3A4 (0.46) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6942653 | 0.76 | POLB (0.34) | RXRARXRBRXRGKDM4EGAA | |
| SCHEMBL29598333 | 0.75 | ALDH1A1 (0.39) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL170839 | 0.75 | ALDH1A1 (0.39) | NPC1ALDH1A1CASP3RAB9ASENP8 | |
| SCHEMBL6198719 | 0.71 | ALDH1A1 (0.43) | NPC1ALDH1A1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148937-B1 | METALLIC COMPLEX CATALYST AND POLYMERIZATION METHODS EMPLOYING SAME | BRIDGESTONE CORP (JP) | 2019-09-18 | — | — | EP | disclosed |
| US-10017595-B2 | Metallic complex catalyst and polymerization methods employing same | BRIDGESTONE CORPORATION (JP) | 2018-07-10 | — | — | US | disclosed |
| US-20170114171-A1 | Metallic Complex Catalyst And Polymerization Methods Employing Same | BRIDGESTONE CORPORATION (JP) | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114171-A1 | Metallic Complex Catalyst And Polymerization Methods Employing Same | C5, C1S, C9 | NPC1 4008/4885ALDH1A1 1981/4885PLA2G1B 974/4885 |
| US-10017595-B2 | Metallic complex catalyst and polymerization methods employing same | C5, C1S, C9 | NPC1 4008/4885ALDH1A1 1981/4885PLA2G1B 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.