Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18763979 | 0.76 | NPC1 (0.36) | RXRBKDM4EGAAMAPTGABRA1 | |
| SCHEMBL4572745 | 0.65 | GABRA1 (0.58) | POLBRXRBKDM4EGAAMAPT | |
| SCHEMBL6940199 | 0.64 | RXRB (0.33) | POLBRXRBKDM4EGAAMAPT | |
| SCHEMBL16117991 | 0.63 | CD44 (0.32) | POLB | |
| SCHEMBL26230931 | 0.62 | GABRA1 (0.55) | POLBRXRBKDM4EGAAMAPT | |
| SCHEMBL30143246 | 0.62 | S1PR1 (0.38) | KDM4EHTR1D | |
| SCHEMBL18763972 | 0.62 | S1PR1 (0.38) | KDM4EHTR1D | |
| SCHEMBL93161 | 0.62 | GABRA1 (0.69) | POLBRXRBKDM4EGAAMAPT | |
| SCHEMBL30083766 | 0.59 | POLB (0.43) | POLBRXRBKDM4EGAAMAPT | |
| SCHEMBL10415675 | 0.59 | GABRA1 (0.65) | POLBRXRBKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157047-B1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP CORP NORTH AMERICA INC (US) | 2003-04-23 | — | — | EP | disclosed |
| US-6479424-B1 | FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS | BP CORPORATION NORTH AMERICA INC. | 2002-11-12 | — | — | US | disclosed |