Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18774721 | 0.90 | HTR1A (0.37) | HTR1AHTR7TACR1ALDH1A1MEN1 | |
| SCHEMBL18763979 | 0.85 | NPC1 (0.36) | ALDH1A1CYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL170839 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KMT2AHPGDSMN1; SMN2CYP17A1 | |
| SCHEMBL29598333 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KMT2AHPGDSMN1; SMN2CYP17A1 | |
| SCHEMBL9873789 | 0.74 | MAPT (0.39) | HTR1AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28134284 | 0.74 | HSD11B1 (0.40) | ALDH1A1CNR2CYP1A2HPGDCYP2C19 | |
| SCHEMBL9441562 | 0.72 | CYP3A4 (0.54) | HTR1AHTR7POLBSMN1; SMN2CYP17A1 | |
| SCHEMBL18763972 | 0.71 | S1PR1 (0.38) | ALDH1A1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL30143246 | 0.71 | S1PR1 (0.38) | ALDH1A1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL8657090 | 0.70 | MAOA (0.36) | ALDH1A1KMT2ACYP1A2CYP2C19PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3148937-B1 | METALLIC COMPLEX CATALYST AND POLYMERIZATION METHODS EMPLOYING SAME | BRIDGESTONE CORP (JP) | 2019-09-18 | — | — | EP | disclosed |
| US-10017595-B2 | Metallic complex catalyst and polymerization methods employing same | BRIDGESTONE CORPORATION (JP) | 2018-07-10 | — | — | US | disclosed |
| US-10017595-B2 | Metallic complex catalyst and polymerization methods employing same | BRIDGESTONE CORPORATION (JP) | 2018-07-10 | — | — | US | disclosed |
| US-20170114171-A1 | Metallic Complex Catalyst And Polymerization Methods Employing Same | BRIDGESTONE CORPORATION (JP) | 2017-04-27 | — | — | US | disclosed |
| US-20170114171-A1 | Metallic Complex Catalyst And Polymerization Methods Employing Same | BRIDGESTONE CORPORATION (JP) | 2017-04-27 | — | — | US | disclosed |
| EP-3148937-A1 | METALLIC COMPLEX CATALYST AND POLYMERIZATION METHODS EMPLOYING SAME | Bridgestone Corporation (JP) | 2017-04-05 | — | — | EP | disclosed |
| WO-2015183770-A1 | METALLIC COMPLEX CATALYST AND POLYMERIZATION METHODS EMPLOYING SAME | BRIDGESTONE CORPORATION (JP) | 2015-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114171-A1 | Metallic Complex Catalyst And Polymerization Methods Employing Same | C5, C1S, C9 | HTR1A 2561/4885HTR7 2423/4885TACR1 3084/4885 |
| US-10017595-B2 | Metallic complex catalyst and polymerization methods employing same | C5, C1S, C9 | HTR1A 2561/4885HTR7 2423/4885TACR1 3084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.