Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Maleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL3632009 | 1.00 | — | — | |
| Fumaric Acid SCHEMBL2548589 | 0.95 | TSHR (0.82) | — | |
| Maleic Acid SCHEMBL10873082 | 0.95 | TSHR (0.82) | — | |
| Fumaric Acid SCHEMBL2548587 | 0.95 | TSHR (0.82) | — | |
| Fumaric Acid SCHEMBL6875 | 0.95 | TSHR (1.00) | — | |
| Fumaric Acid SCHEMBL2046433 | 0.95 | TSHR (1.00) | — | |
| Fumaric Acid SCHEMBL3998225 | 0.95 | — | — | |
| Maleic Acid SCHEMBL20487516 | 0.95 | TSHR (1.00) | — | |
| Fumaric Acid SCHEMBL615 | 0.95 | — | — | |
| Maleic Acid SCHEMBL2046430 | 0.95 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120059436-A | High-transparency scratch-resistant polycarbonate material | 厦门天宇新材料科技有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-119684852-A | Laminated aluminum sheet for drilling printed circuit board and preparation method thereof | 深圳市柳鑫实业股份有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-118440478-B | Biodegradable functional plastic particles and preparation method thereof | 山东蓝海晶体科技有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-118530571-A | Near infrared absorption electromagnetic shielding polycarbonate material with reaction capacity increasing function and preparation method thereof | 厦门天宇新材料科技有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-118440478-A | Biodegradable functional plastic particles and preparation method thereof | 山东蓝海晶体科技有限公司 | 2024-08-06 | — | — | CN | claimed |
| CN-118406358-A | High-toughness silicon-containing hydrophobic polycarbonate material and preparation method thereof | 厦门天宇新材料科技有限公司 | 2024-07-30 | — | — | CN | claimed |
| CN-118271820-A | Polycarbonate diol modified polycarbonate matrix composite material and preparation method thereof | 厦门天宇新材料科技有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118271499-A | Modifier for enhancing hydrophobicity of polycarbonate by utilizing perfluoroalkyl alcohol, preparation method and application thereof | 厦门天宇新材料科技有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118146733-A | Flame-retardant interior composite material and preparation method thereof | 中国科学院大连化学物理研究所 | 2024-06-07 | — | — | CN | claimed |
| CN-118109004-A | External protection elastomer material, preparation and application | 中国科学院大连化学物理研究所 | 2024-05-31 | — | — | CN | claimed |
| US-4840849-A | CHLOROSULFONATED POLYOLEFIN CONTAINING LEAD COMPOUND AND PEROXIDE | TOSOH CORPORATION (JP) | 1989-06-20 | — | — | US | claimed |
| EP-0145378-B1 | PROCESS FOR PRODUCING OPTICAL FIBER FOR OPTICAL TRANSMISSION | SUMITOMO ELECTRIC INDUSTRIES LIMITED (JP) | 1988-04-20 | — | — | EP | claimed |
| US-4654238-A | EXTRUSION COATING A METAL INSERT WITH VINYL CHLORIDE RESIN USING ACRYLATE ADHESIVE | TOYODA GOSEI CO., LTD. (JP) | 1987-03-31 | — | — | US | claimed |
| US-4540597-A | CROSSLINKING POLYAMIDE OR POLYESTER COATING WITH LEAD CATALYST | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1985-09-10 | — | — | US | claimed |
| EP-0145378-A2 | Process for producing optical fiber for optical transmission | SUMITOMO ELECTRIC INDUSTRIES LIMITED (JP) | 1985-06-19 | — | — | EP | claimed |
| US-4434251-A | Cross-linked polyvinyl chloride resin foam and method of manufacturing the same | THE FURUKAWA ELECTRIC CO., LTD. (JP) | 1984-02-28 | — | — | US | claimed |
| EP-0053190-A1 | CROSSLINKED VINYL CHLORIDE RESIN FOAM AND PROCESS FOR MANUFACTURING THE SAME | THE FURUKAWA ELECTRIC CO., LTD. (JP) | 1982-06-09 | — | — | EP | claimed |
| US-4329247-A | ETHYLENE GLYCOL MONOALKYL ETHERS OR MONOALKYL ETHER ACETATES AS SOLVENT ALONG WITH SODIUM HYPOCHLORITE OR CALCIUM HYPOCHLORITE IN FUMED SILICA | PDI, INC. (US) | 1982-05-11 | — | — | US | claimed |
| US-4119587-A | Adhesive compositions comprising (a) halogenated polyolefin (b) aromatic nitroso compound and (c) lead salts | LORD CORPORATION (US) | 1978-10-10 | — | — | US | claimed |
| US-4081493-A | Resin composition having resistance to hydrolysis | KAO SOAP CO., LTD. (JA) | 1978-03-28 | — | — | US | claimed |