Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768424 | 0.93 | AKR1C3 (0.49) | AKR1C3AR | |
| SCHEMBL18768429 | 0.92 | KDM4E (0.47) | AKR1C3DRD2AR | |
| SCHEMBL18768423 | 0.92 | AKR1C3 (0.46) | AKR1C3ARHDAC6 | |
| SCHEMBL18768624 | 0.90 | DRD3 (0.49) | DRD2DRD3 | |
| SCHEMBL18768363 | 0.88 | AR (0.48) | AKR1C3DRD2AR | |
| SCHEMBL18768567 | 0.88 | MDM2 (0.49) | MDM2 | |
| SCHEMBL18768565 | 0.86 | DRD2 (0.46) | AKR1C3DRD2AR | |
| SCHEMBL18768427 | 0.86 | — | — | |
| SCHEMBL18768569 | 0.85 | OPRM1 (0.49) | DRD2DRD3 | |
| SCHEMBL18768360 | 0.84 | AKR1C3 (0.46) | AKR1C3DRD2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |