Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768424 | 0.93 | AKR1C3 (0.49) | AKR1C3ARSLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL18768571 | 0.92 | AKR1C3 (0.47) | DRD2AKR1C3AR | |
| SCHEMBL18768565 | 0.90 | DRD2 (0.46) | DRD4DRD2AKR1C3ARSLC6A2 | |
| SCHEMBL18768569 | 0.88 | OPRM1 (0.49) | KDM4EALDH1A1MAPTDRD4DRD2 | |
| SCHEMBL18768423 | 0.88 | AKR1C3 (0.46) | AKR1C3ARSLC6A4 | |
| SCHEMBL18768624 | 0.86 | DRD3 (0.49) | DRD4DRD2OPRM1SIGMAR1 | |
| SCHEMBL18768363 | 0.86 | AR (0.48) | KDM4EDRD4DRD2OPRM1AKR1C3 | |
| SCHEMBL18768360 | 0.82 | AKR1C3 (0.46) | KDM4EATMDRD4DRD2AKR1C3 | |
| SCHEMBL18768568 | 0.81 | ACHE (0.45) | AKR1C3ARCXCR4 | |
| SCHEMBL18768357 | 0.80 | ACHE (0.52) | SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |