Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768365 | 0.91 | AKR1C3 (0.52) | KMT2AMEN1NPC1AKR1C3SLC6A2 | |
| SCHEMBL18768629 | 0.88 | GSK3B (0.59) | KMT2AMEN1SLC6A2SLC6A4GSK3B | |
| SCHEMBL18767961 | 0.86 | AKR1C3 (0.57) | KMT2AMEN1NPC1AKR1C3MTNR1A | |
| SCHEMBL18768559 | 0.80 | GSK3B (0.60) | NPC1SLC6A2SLC6A4RAB9AGSK3B | |
| SCHEMBL18767964 | 0.78 | SLC6A2 (0.59) | AKR1C3SLC6A2SLC6A4KDM4EDRD2 | |
| SCHEMBL18767313 | 0.78 | NPC1 (0.52) | KMT2AMEN1NPC1AKR1C3MTNR1A | |
| SCHEMBL18767324 | 0.78 | NPC1 (0.52) | KMT2AMEN1NPC1AKR1C3SLC6A2 | |
| SCHEMBL18766905 | 0.77 | KMT2A (0.54) | KMT2AMEN1KDM4EMAPTSIGMAR1 | |
| SCHEMBL18768573 | 0.76 | SLC6A2 (0.66) | SLC6A2SLC6A4KDM4ENAMPTGSK3B | |
| SCHEMBL6885051 | 0.76 | KDM4E (0.67) | AKR1C3KDM4EDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |