Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18766917 | 0.87 | KMT2A (0.55) | KMT2ASIGMAR1KDM4EPKMDRD2 | |
| SCHEMBL29725632 | 0.86 | MEN1 (0.57) | KMT2ASIGMAR1MEN1MAPTKDM4E | |
| SCHEMBL18768210 | 0.84 | ACACB (0.47) | KMT2AMEN1TGFBR1MAPTKDM4E | |
| SCHEMBL18766901 | 0.82 | MAPT (0.46) | KMT2AMEN1TGFBR1MAPTKDM4E | |
| SCHEMBL16002968 | 0.77 | SIGMAR1 (0.62) | KMT2ASIGMAR1MEN1MAPTKDM4E | |
| SCHEMBL18768635 | 0.77 | KMT2A (0.51) | KMT2ASIGMAR1MEN1MAPTKDM4E | |
| SCHEMBL13826659 | 0.76 | SIGMAR1 (0.60) | KMT2ASIGMAR1MEN1MAPTKDM4E | |
| SCHEMBL16825188 | 0.76 | TGFBR1 (0.56) | KMT2AMEN1TGFBR1KDM4EPKM | |
| SCHEMBL1295318 | 0.75 | ALDH1A1 (0.47) | KMT2AMEN1KDM4EPOLBCACNA1B | |
| SCHEMBL29725623 | 0.75 | ACHE (0.61) | KMT2ASIGMAR1MEN1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |