Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21160967 | 1.00 | HRH3 (0.36) | HRH3KCNH2RECQLGAAHPGD | |
| SCHEMBL633803 | 1.00 | HRH3 (0.36) | HRH3KCNH2RECQLGAAHPGD | |
| SCHEMBL6496552 | 1.00 | HRH3 (0.36) | HRH3KCNH2RECQLGAAHPGD | |
| SCHEMBL19649547 | 0.98 | RECQL (0.38) | HRH3KCNH2RECQLGAAHPGD | |
| SCHEMBL16627509 | 0.98 | RECQL (0.38) | HRH3KCNH2RECQLGAAHPGD | |
| SCHEMBL10996925 | 0.97 | HRH3 (0.36) | HRH3KCNH2GAAHPGDALDH1A1 | |
| SCHEMBL7021706 | 0.95 | HRH3 (0.35) | HRH3KCNH2RECQLGAAHPGD | |
| SCHEMBL16254919 | 0.95 | HRH3 (0.35) | HRH3KCNH2RECQLGAAHPGD | |
| SCHEMBL30341037 | 0.95 | HRH3 (0.35) | HRH3KCNH2RECQLGAAHPGD | |
| SCHEMBL5872327 | 0.95 | HRH3 (0.38) | HRH3KCNH2RECQLGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981957-B2 | Synthetic process | THE UNIVERSITY OF LIVERPOOL (GB) | 2018-05-29 | — | — | US | disclosed |
| US-20170107208-A1 | SYNTHETIC PROCESS | THE UNIVERSITY OF LIVERPOOL (GB) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170107208-A1 | SYNTHETIC PROCESS | PIR, SRM, SMS | HRH3 25/4885KCNH2 801/4885RECQL 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.