Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18769589 | 0.78 | SLC6A4 (0.38) | KDM1ASLC6A3SLC6A4SLC6A2 | |
| SCHEMBL8365226 | 0.66 | SLC6A3 (0.44) | MAOBMAOALIG1SLC6A3SLC6A4 | |
| SCHEMBL8254657 | 0.66 | SLC6A3 (0.48) | MAOBMAOASLC6A3 | |
| Hydrochloric Acid SCHEMBL2310506 | 0.65 | SLC6A3 (0.47) | MAOBMAOASLC6A3 | |
| SCHEMBL16422952 | 0.64 | MAOB (0.48) | MAOBMAOAKDM1ALIG1SLC6A3 | |
| SCHEMBL10248851 | 0.63 | MAOB (0.42) | MAOBMAOAKDM1ALIG1SLC6A3 | |
| SCHEMBL21564625 | 0.63 | MAOB (0.57) | MAOBMAOAKDM1ASLC6A3 | |
| SCHEMBL13361601 | 0.62 | SLC6A3 (0.48) | MAOBMAOASLC6A3SLC6A4SLC6A2 | |
| SCHEMBL18306930 | 0.62 | OPRM1 (0.50) | SLC6A3SLC6A4SLC6A2HSD11B1 | |
| SCHEMBL2780627 | 0.62 | SLC6A3 (0.53) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017065473-A1 | OXADIAZOLE AMINE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2017-04-20 | — | — | WO | disclosed |