Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154699 | 0.95 | OPRM1 (0.50) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL26929227 | 0.94 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL11648759 | 0.93 | SLC6A3 (0.52) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL7824744 | 0.90 | OPRM1 (0.53) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL31322237 | 0.82 | DRD2 (0.58) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL615480 | 0.80 | DRD2 (0.66) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL3640272 | 0.80 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| Ethoxycarbonyl Group SCHEMBL28100919 | 0.79 | OPRM1 (0.39) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL613615 | 0.79 | OPRM1 (0.45) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| Hydrochloric Acid SCHEMBL1765160 | 0.79 | DRD2 (0.63) | OPRM1OPRD1OPRK1OPRL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122071411-A | Method for forming ester by oxidizing and breaking carbon-carbon bond by tertiary alcohol | 中国科学院大连化学物理研究所 | 2026-05-22 | — | — | CN | disclosed |
| CN-113636977-B | Synthesis method of 2-aryl benzazepine and derivatives thereof | 温州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-112110801-B | Synthetic method of gamma-aryl substituted ketone compound | 浙江工业大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-110218227-B | Method for preparing aryl ketone derivative | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |
| CN-113636977-A | Synthesis method of 2-aryl benzazepine and derivatives thereof | 温州大学 | 2021-11-12 | — | — | CN | disclosed |
| WO-2021071843-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | Pipeline Therapeutics, Inc. (US) | 2021-04-15 | — | — | WO | disclosed |
| CN-112110801-A | Method for synthesizing gamma-aryl substituted ketone compound | 浙江工业大学 | 2020-12-22 | — | — | CN | disclosed |
| CN-108285415-B | Preparation method of 1, 5-diketone compound | 浙江师范大学 | 2020-06-02 | — | — | CN | disclosed |
| CN-108299198-B | Preparation method of 1, 4-diketone compound | 浙江师范大学 | 2020-04-17 | — | — | CN | disclosed |
| CN-110218227-A | A method of preparing aryl ketone derivatives | 苏州大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-108299198-A | A kind of preparation method of 1,4- dione compounds | 浙江师范大学 | 2018-07-20 | — | — | CN | disclosed |
| CN-108285415-A | A kind of preparation method of 1,5- dione compounds | 浙江师范大学 | 2018-07-17 | — | — | CN | disclosed |
| WO-2018107415-A1 | HYDROXY ISOXAZOLE COMPOUNDS USEFUL AS GPR120 AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2018-06-21 | — | — | WO | disclosed |
| EP-2804868-B1 | PYRAN-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS | VERTEX PHARMA (US) | 2017-04-12 | — | — | EP | disclosed |
| EP-2686325-B1 | MORPHOLINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS | VERTEX PHARMA (US) | 2016-12-14 | — | — | EP | disclosed |