Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18770123 | 0.86 | KMT2A (0.55) | CCR2KMT2A | |
| SCHEMBL20539090 | 0.86 | CCR2 (0.49) | CCR2 | |
| SCHEMBL18770127 | 0.83 | CA2 (0.54) | CCR2KMT2A | |
| SCHEMBL18770111 | 0.78 | CCR2 (0.47) | CCR2 | |
| SCHEMBL18770107 | 0.77 | CCR2 (0.46) | CCR2KMT2A | |
| SCHEMBL18770136 | 0.76 | CCR2 (0.43) | CCR2KMT2A | |
| SCHEMBL18770126 | 0.75 | GAA (0.52) | CCR2KMT2A | |
| SCHEMBL18770144 | 0.74 | CCR2 (0.48) | CCR2 | |
| SCHEMBL18770105 | 0.74 | CCR2 (0.55) | CCR2 | |
| SCHEMBL18770134 | 0.73 | CCR2 (0.56) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365325-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NITROXYL DONORS | Cardioxyl Pharmaceuticals Inc. (US) | 2018-08-29 | — | — | EP | claimed |
| WO-2017070084-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NITROXYL DONORS | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2017-04-27 | — | — | WO | claimed |
| US-10730828-B2 | N-hydroxylsulfonamide derivatives as nitroxyl donors | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2020-08-04 | — | — | US | disclosed |
| US-10730828-B2 | N-hydroxylsulfonamide derivatives as nitroxyl donors | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2020-08-04 | — | — | US | disclosed |
| US-20180305304-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NITROXYL DONORS | THE JOHNS HOPKINS UNIVERSITY | 2018-10-25 | — | — | US | disclosed |
| EP-3365325-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NITROXYL DONORS | Cardioxyl Pharmaceuticals Inc. (US) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017070084-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NITROXYL DONORS | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2017-04-27 | — | — | WO | disclosed |
| WO-2017070084-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NITROXYL DONORS | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2017-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180305304-A1 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NITROXYL DONORS | TNNI3, TNNT2, TNNC1 | CCR2 4285/4885KMT2A 4358/4885 |
| US-10730828-B2 | N-hydroxylsulfonamide derivatives as nitroxyl donors | TNNI3, TNNT2, TNNC1 | CCR2 4285/4885KMT2A 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.