Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.34 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18771933 | 0.92 | TLR8 (0.34) | TLR8TLR7ERN1CYP3A4OTUD7B | |
| SCHEMBL18771979 | 0.87 | TLR8 (0.44) | TLR8TLR7GALR1 | |
| SCHEMBL19265546 | 0.85 | TLR8 (0.33) | TLR8TLR7ERN1CYP3A4OTUD7B | |
| SCHEMBL18772024 | 0.84 | TLR8 (0.56) | TLR8TLR7 | |
| SCHEMBL18772002 | 0.84 | HPGD (0.37) | TLR8TLR7LMNAHPGDTSHR | |
| SCHEMBL18771974 | 0.83 | MMP2 (0.45) | TLR8TLR7HPGDTSHR | |
| SCHEMBL18772117 | 0.83 | KDM4E (0.39) | TLR8TLR7LMNAHPGD | |
| SCHEMBL18771963 | 0.83 | MMP2 (0.41) | TLR8TLR7HPGD | |
| SCHEMBL18771997 | 0.81 | TLR8 (0.45) | TLR8TLR7LMNAHPGDTSHR | |
| SCHEMBL19265526 | 0.81 | TLR8 (0.40) | TLR8TLR7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159337-A2 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-04-26 | — | — | EP | disclosed |