Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.46 |
| ▸ | HTR5A | P47898 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1880790 | 0.93 | KDM4E (0.46) | APAF1PABPC1CASP6CASP8L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL1872849 | 0.91 | OPRM1 (0.53) | OPRM1OPRD1OPRK1HTR5AMEN1 | |
| Trifluoroacetic Acid SCHEMBL1876945 | 0.89 | ALDH1A1 (0.49) | OPRM1OPRD1OPRK1HTR5AHTR1A | |
| Trifluoroacetic Acid SCHEMBL1879968 | 0.87 | OPRM1 (0.45) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL1877050 | 0.86 | HDAC1 (0.46) | OPRM1OPRD1OPRK1HDAC1ADRB1 | |
| Trifluoroacetic Acid SCHEMBL1878025 | 0.86 | L3MBTL1 (0.46) | OPRM1OPRD1OPRK1HTR2AL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL1874425 | 0.85 | HTR5A (0.43) | OPRM1OPRD1OPRK1HTR5AL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL1875954 | 0.84 | CACNA1B (0.42) | MMP13 | |
| Trifluoroacetic Acid SCHEMBL1876324 | 0.84 | OPRM1 (0.41) | OPRM1OPRD1OPRK1GRIN2DGRIN3B | |
| SCHEMBL12634004 | 0.83 | CDK1 (0.45) | OPRM1OPRD1OPRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939528-B2 | Heterocycle compounds | GLAXOSMITHKLINE LLC (US) | 2011-05-10 | — | — | US | disclosed |