SCHEMBL18779487

SCHEMBL18779487

CCn1c2c(C)cccc2c2c(C)c(C)c(C)c(C)c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.40
FTO Q9C0B1 1/20 0.40
ATM Q13315 2/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 4/20 0.37
ALDH1A1 P00352 3/20 0.37
LMNA P02545 2/20 0.37
TSHR P16473 2/20 0.37
CNR2 P34972 2/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
GAA P10253 1/20 0.35
KDM4E B2RXH2 2/20 0.35
AHR P35869 1/20 0.34
NPC1 O15118 1/20 0.34
HCRTR1 O43613 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26073705 0.83 ALKBH5 (0.48) ALKBH5FTOATMMEN1KMT2A
SCHEMBL19829059 0.77 ALDH1A1 (0.50) MEN1KMT2AL3MBTL1TDP1MAPT
SCHEMBL18385116 0.74 KDM4E (0.37) KDM4E
SCHEMBL27604178 0.73 MEN1 (0.38) ALKBH5FTOATMMEN1KMT2A
SCHEMBL26146571 0.72 KDM4E (0.36) KDM4E
SCHEMBL26146575 0.72 KDM4E (0.36) KDM4E
SCHEMBL26146573 0.72 KDM4E (0.36) KDM4E
SCHEMBL25491299 0.72 ALDH1A1 (0.49) MEN1KMT2AL3MBTL1TDP1MAPT
SCHEMBL8178240 0.71 ALKBH5 (0.59) ALKBH5FTOATMMEN1KMT2A
SCHEMBL19271287 0.71 ALDH1A1 (0.47) ALKBH5FTOATMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170117488-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-04-27 US disclosed