SCHEMBL26073705

SCHEMBL26073705

CCn1c2c(C)cccc2c2cccc(C)c21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.48
FTO Q9C0B1 1/20 0.48
CYP2A6 P11509 2/20 0.46
CYP1A2 P05177 1/20 0.46
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
ALDH1A1 P00352 5/20 0.44
MAPT P10636 4/20 0.44
LMNA P02545 1/20 0.44
TSHR P16473 2/20 0.43
GAA P10253 1/20 0.41
CNR2 P34972 3/20 0.41
HSD17B10 Q99714 2/20 0.39
KDM4E B2RXH2 1/20 0.39
NSD2 O96028 1/20 0.39
HTT P42858 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8178240 0.86 ALKBH5 (0.59) ALKBH5FTOCYP1A2ATML3MBTL1
SCHEMBL19271287 0.86 ALDH1A1 (0.47) ALKBH5FTOCYP2A6CYP1A2ATM
SCHEMBL18779487 0.83 ALKBH5 (0.40) ALKBH5FTOCYP2A6CYP1A2ATM
SCHEMBL18415775 0.80 KDM4E (0.39) ALKBH5FTOATML3MBTL1MEN1
SCHEMBL19271267 0.79 ALKBH5 (0.44) ALKBH5FTOCYP2A6CYP1A2ATM
SCHEMBL19271312 0.78 KDM5A (0.45) ALKBH5FTO
SCHEMBL19271296 0.78 MAOA (0.48) ALKBH5FTOALDH1A1LMNAHTT
SCHEMBL19271266 0.77 FABP4 (0.52) MEN1KMT2AALDH1A1HSD17B10KDM4E
SCHEMBL9581033 0.77 GAA (0.40) ALKBH5FTOCYP2A6CYP1A2ATM
SCHEMBL27784775 0.76 ALKBH5 (0.41) ALKBH5FTOATML3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 ALKBH5 2937/4885FTO 814/4885CYP2A6 2496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.