Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149523 | 0.80 | KDM4E (0.55) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL9778947 | 0.78 | ALDH1A1 (0.43) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL28750464 | 0.77 | SMN1; SMN2 (0.45) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL18779487 | 0.73 | ALKBH5 (0.40) | MEN1KMT2AATMUSP2KEAP1 | |
| SCHEMBL26073705 | 0.73 | ALKBH5 (0.48) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL8178240 | 0.73 | ALKBH5 (0.59) | MEN1KMT2AATMUSP2MAPT | |
| SCHEMBL1149724 | 0.71 | KDM4E (0.48) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL8931397 | 0.68 | TLR8 (0.41) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL1150214 | 0.68 | MAPT (0.40) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL19271284 | 0.68 | ALDH1A1 (0.42) | MEN1KMT2AATMUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1531527-A | Carbazole derivatives and their use as neuropeptide Y5 receptor ligands | — | 2004-09-22 | — | — | CN | disclosed |