Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23956955 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1LMNADDB1 | |
| SCHEMBL22085965 | 0.82 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1P4HB | |
| SCHEMBL7332893 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1LMNASYK | |
| SCHEMBL2811577 | 0.78 | LMNA (0.48) | ALDH1A1MAPK1L3MBTL1LMNAP4HB | |
| SCHEMBL31480725 | 0.77 | SYK (0.39) | ALDH1A1SYKDDB1CRBNMEN1 | |
| SCHEMBL8779517 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1LMNADDB1 | |
| SCHEMBL31480812 | 0.77 | SYK (0.51) | MAPK1L3MBTL1LMNASYKKLK7 | |
| SCHEMBL22481266 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1LMNASYK | |
| SCHEMBL12990128 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1LMNASYK | |
| SCHEMBL23956985 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPK1L3MBTL1SYKDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213492-A1 | DRUG-CARRYING MACROMOLECULE AND PREPARATION METHOD THEREFOR | 上海森辉医药有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |
| WO-2017069270-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | 大正製薬株式会社 | 2017-04-27 | — | — | WO | disclosed |