SCHEMBL18783136

SCHEMBL18783136

CC(C)(C)c1ccc(S(C)(C)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
TSHR P16473 3/20 0.50
LMNA P02545 3/20 0.48
TYR P14679 1/20 0.48
HSD11B1 P28845 3/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 3/20 0.42
HPGD P15428 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C19 P33261 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
GMNN O75496 1/20 0.42
DRD1 P21728 1/20 0.42
DRD3 P35462 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18736607 0.85 GRIA4 (0.45) ALDH1A1TSHRLMNATYRHSD11B1
SCHEMBL19743180 0.83 ALDH1A1 (0.56) ALDH1A1TSHRLMNATYRHSD11B1
SCHEMBL12404911 0.83 ALDH1A1 (0.56) ALDH1A1TSHRLMNATYRHSD11B1
SCHEMBL20718605 0.80 ALDH1A1 (0.58) ALDH1A1TSHRLMNATYRHSD11B1
SCHEMBL3852987 0.79 ALDH1A1 (0.52) ALDH1A1TSHRLMNATYRHSD11B1
SCHEMBL1107981 0.79 ALDH1A1 (0.64) ALDH1A1TSHRLMNAHSD11B1GAA
SCHEMBL424728 0.78 TSHR (0.73) ALDH1A1TSHRLMNATYRMAPT
SCHEMBL19743211 0.77 KIF11 (0.52) ALDH1A1TSHRLMNATYRHSD11B1
Fluoride SCHEMBL915073 0.77 ALDH1A1 (0.50) ALDH1A1TSHRLMNATYRHSD11B1
SCHEMBL24717204 0.77 ALDH1A1 (0.45) ALDH1A1TSHRLMNATYRHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10729820-B2 Methods and processes for application of drug delivery polymeric coatings ARISTE MEDICAL, LLC (US) 2020-08-04 US disclosed
US-10439225-B2 Lithium electrode and lithium battery including same LG CHEM, LTD. (KR) 2019-10-08 US disclosed
US-20170117551-A1 LITHIUM ELECTRODE AND LITHIUM BATTERY INCLUDING SAME LG CHEM, LTD. (KR) 2017-04-27 US disclosed