Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3852987 | 0.98 | ALDH1A1 (0.52) | ALDH1A1HSD11B1TSHRLMNATYR | |
| SCHEMBL19743180 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HSD11B1TSHRLMNATYR | |
| SCHEMBL18783136 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HSD11B1TSHRLMNATYR | |
| SCHEMBL12404911 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HSD11B1TSHRLMNATYR | |
| SCHEMBL66108 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HSD11B1TSHRLMNAGAA | |
| SCHEMBL20718605 | 0.74 | ALDH1A1 (0.58) | ALDH1A1HSD11B1TSHRLMNATYR | |
| SCHEMBL1107981 | 0.73 | ALDH1A1 (0.64) | ALDH1A1HSD11B1TSHRLMNAGAA | |
| SCHEMBL13220215 | 0.73 | ALDH1A1 (0.57) | ALDH1A1HSD11B1TSHRLMNAGAA | |
| SCHEMBL424728 | 0.72 | TSHR (0.73) | ALDH1A1TSHRLMNATYRMAPT | |
| SCHEMBL19743211 | 0.71 | KIF11 (0.52) | ALDH1A1HSD11B1TSHRLMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | claimed |
| EP-2046735-B1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDES AS FLUORINATING AGENTS | UBE INDUSTRIES (JP) | 2015-05-06 | — | — | EP | claimed |
| US-20140235898-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | UBE INDUSTRIES, LTD. (JP) | 2014-08-21 | — | — | US | claimed |
| US-8710270-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2014-04-29 | — | — | US | claimed |
| US-20110009672-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | IM&T RESEARCH, INC. (US) | 2011-01-13 | — | — | US | claimed |
| EP-2046735-A2 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM&T Research, Inc. (US) | 2009-04-15 | — | — | EP | claimed |
| US-7381846-B2 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-06-03 | — | — | US | claimed |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-02-14 | — | — | US | claimed |
| WO-2008014345-A2 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM & T RESEARCH, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| EP-2046735-B1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDES AS FLUORINATING AGENTS | UBE INDUSTRIES (JP) | 2015-05-06 | — | — | EP | disclosed |
| US-20140235898-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | UBE INDUSTRIES, LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| US-8710270-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2014-04-29 | — | — | US | disclosed |
| US-7919635-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2011-04-05 | — | — | US | disclosed |
| EP-2046735-A2 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM&T Research, Inc. (US) | 2009-04-15 | — | — | EP | disclosed |
| US-7501543-B2 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | IM&T RESEARCH, INC. (US) | 2009-03-10 | — | — | US | disclosed |
| US-20080221364-A1 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | IM&T RESEARCH, INC. (US) | 2008-09-11 | — | — | US | disclosed |
| US-7381846-B2 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-02-14 | — | — | US | disclosed |
| WO-2008014345-A2 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM & T RESEARCH, INC. (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235898-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | PFAS, FRS2, FBL | ALDH1A1 2581/4885HSD11B1 4403/4885TSHR 952/4885 |
| US-20110009672-A1 | Substituted Phenylsulfur Trifluoride and Other Like Fluorinating Agents | PFAS, FRS2, FBL | ALDH1A1 2581/4885HSD11B1 4403/4885TSHR 952/4885 |
| US-20080221364-A1 | Bis[2,6-bis(methoxymethyl)phenyl]disulfide; intermediates | PFAS, STS, SCLY | ALDH1A1 2010/4885HSD11B1 2240/4885TSHR 1750/4885 |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | TST, DDT, ESD | ALDH1A1 2815/4885HSD11B1 3161/4885TSHR 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.