SCHEMBL18790907

SCHEMBL18790907

CC(C)(C)Cc1cccc(-c2ccnc(-c3ccccc3)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ASIC3 Q9UHC3 2/20 0.47
PIM1 P11309 1/20 0.43
WNT3A P56704 3/20 0.41
HTR1A P08908 1/20 0.40
HTR7 P34969 1/20 0.40
GGPS1 O95749 2/20 0.39
TGFBR1 P36897 2/20 0.39
PRMT6 Q96LA8 1/20 0.39
KDM4A O75164 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
PRKCI P41743 1/20 0.38
SREBF2 Q12772 1/20 0.37
SMO Q99835 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18625006 0.88 ASIC3 (0.47) ASIC3PIM1WNT3AHTR1AHTR7
SCHEMBL9975654 0.87 ASIC3 (0.53) ASIC3WNT3AHTR1AHTR7SREBF2
SCHEMBL22134624 0.85 ASIC3 (0.44) ASIC3WNT3AHTR1AHTR7GGPS1
SCHEMBL18643801 0.85 TGFBR1 (0.45) WNT3AHTR7TGFBR1
SCHEMBL4402444 0.81 HRH3 (0.52) HTR1AHTR7TGFBR1
SCHEMBL18790955 0.81 CYP11B1 (0.47) WNT3AGGPS1
SCHEMBL197793 0.80 GGPS1 (0.44) GGPS1PRMT6PRKCI
SCHEMBL4402446 0.79 PRKCI (0.61) GGPS1PRMT6PRKCI
SCHEMBL18790906 0.79 ASIC3 (0.44) ASIC3PIM1WNT3AHTR1AHTR7
SCHEMBL18624998 0.78 ASIC3 (0.44) ASIC3PIM1WNT3AHTR1AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3159350-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-04-26 EP disclosed