Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2734459 | 0.84 | HRH3 (0.47) | HRH3HTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4472579 | 0.82 | HRH3 (0.54) | HRH3HTTSMN1; SMN2FFAR1CYP1A2 | |
| SCHEMBL8270139 | 0.81 | HRH3 (0.56) | HRH3HTTSMN1; SMN2FFAR1CYP1A2 | |
| SCHEMBL18729495 | 0.81 | BRS3 (0.51) | HTTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL18790907 | 0.81 | ASIC3 (0.47) | HTR1AHTR7TGFBR1 | |
| SCHEMBL22387811 | 0.79 | CYP1A2 (0.53) | HRH3FFAR1CYP1A2CYP2D6CYP19A1 | |
| SCHEMBL2482401 | 0.79 | HRH3 (0.54) | HRH3HTTSMN1; SMN2FFAR1CYP1A2 | |
| SCHEMBL197793 | 0.78 | GGPS1 (0.44) | — | |
| SCHEMBL22134624 | 0.78 | ASIC3 (0.44) | HCRTR1HCRTR2HTR1AHTR7 | |
| SCHEMBL2696099 | 0.78 | HRH3 (0.56) | HRH3HTTSMN1; SMN2FFAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827615-B2 | Nitrogen-containing compound, electronic element and electronic device | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2023-11-28 | — | — | US | disclosed |
| US-20220220049-A1 | ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2022-07-14 | — | — | US | disclosed |
| US-11203584-B2 | Nitrogen-containing compound, electronic element and electronic device | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2021-12-21 | — | — | US | disclosed |
| US-20210206741-A1 | Nitrogen-containing compound, electronic element and electronic device | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2021-07-08 | — | — | US | disclosed |
| US-9818951-B2 | Polycyclic compound and organic electronic device comprising the same | LG CHEM, LTD. (KR) | 2017-11-14 | — | — | US | disclosed |
| US-20150353495-A1 | NICOTINAMIDES AS JAK KINASE MODULATORS | ALEXION PHARMACEUTICALS, INC. | 2015-12-10 | — | — | US | disclosed |
| US-9102625-B2 | Nicotinamides as JAK kinase modulators | PORTOLA PHARMACEUTICALS, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-20120108566-A1 | NICOTINAMIDES AS JAK KINASE MODULATORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220049-A1 | ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS | HCN2, EPCAM, EFNA1 | HRH3 913/4885HTT 258/4885SMN1; SMN2 2482/4885 |
| US-20210206741-A1 | Nitrogen-containing compound, electronic element and electronic device | NOS1, PRMT1, MNS1 | HRH3 340/4885HTT 2638/4885SMN1; SMN2 1446/4885 |
| US-11827615-B2 | Nitrogen-containing compound, electronic element and electronic device | NOS1, PRMT1, MNS1 | HRH3 340/4885HTT 2638/4885SMN1; SMN2 1446/4885 |
| US-11203584-B2 | Nitrogen-containing compound, electronic element and electronic device | NOS1, PRMT1, MNS1 | HRH3 340/4885HTT 2638/4885SMN1; SMN2 1446/4885 |
| US-20150353495-A1 | NICOTINAMIDES AS JAK KINASE MODULATORS | JAK2, JAK1, NADK | HRH3 1134/4885HTT 1328/4885SMN1; SMN2 3820/4885 |
| US-20120108566-A1 | NICOTINAMIDES AS JAK KINASE MODULATORS | JAK2, JAK1, NADK | HRH3 1134/4885HTT 1328/4885SMN1; SMN2 3820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.