SCHEMBL9975654

SCHEMBL9975654

CC(C)(C)Cc1ccnc(-c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ASIC3 Q9UHC3 2/20 0.53
LOXL2 Q9Y4K0 2/20 0.44
HTR1A P08908 1/20 0.43
HTR7 P34969 1/20 0.43
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.40
WNT3A P56704 1/20 0.40
SHMT1 P34896 1/20 0.39
FFAR1 O14842 1/20 0.39
HCRTR1 O43613 3/20 0.39
HCRTR2 O43614 3/20 0.39
NR3C2 P08235 1/20 0.38
NPC1 O15118 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22134624 0.91 ASIC3 (0.44) ASIC3LOXL2HTR1AHTR7PDCD1
SCHEMBL26417417 0.90 ASIC3 (0.50) ASIC3LOXL2HTR1AHTR7CYP11B1
SCHEMBL18790907 0.87 ASIC3 (0.47) ASIC3HTR1AHTR7WNT3ASREBF2
SCHEMBL12747271 0.85 CCR1 (0.43) LOXL2NR3C2NPC1HTTRAB9A
SCHEMBL26172508 0.85 LOXL2 (0.41) ASIC3LOXL2KDM4EALDH1A1NPC1
SCHEMBL22134626 0.84 PDCD1 (0.42) ASIC3LOXL2HTR1AHTR7CYP11B1
SCHEMBL18625006 0.84 ASIC3 (0.47) ASIC3HTR1AHTR7CYP11B1CYP11B2
SCHEMBL23879666 0.81 HTR7 (0.43) ASIC3LOXL2HTR7PDCD1CD274
SCHEMBL10271516 0.80 ASIC3 (0.53) ASIC3LOXL2HTR1AHTR7CYP11B1
SCHEMBL23898441 0.80 TDP1 (0.48) KDM4EALDH1A1NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839142-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-12-05 US disclosed
US-11832508-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2023-11-28 US disclosed
US-11832508-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2023-11-28 US disclosed
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11765966-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-19 US disclosed
US-11744141-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-08-10 US disclosed
US-11697662-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-20230006151-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-05 US disclosed
US-20150243913-A1 Organic Electroluminescence Device UDC IRELAND LTD (IE) 2015-08-27 US disclosed
US-8945725-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2015-02-03 US disclosed
US-8945725-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2015-02-03 US disclosed
US-20140135498-A1 ORGANIC ELECTROLUMINESCENCE DEVICE UDC IRELAND LTD (IE) 2014-05-15 US disclosed
US-20140135498-A1 ORGANIC ELECTROLUMINESCENCE DEVICE UDC IRELAND LTD (IE) 2014-05-15 US disclosed
US-20120153816-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153816-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
WO-2011024986-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 WO disclosed
US-20110049496-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110049496-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230006151-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, LEF1 ASIC3 835/4885LOXL2 16/4885HTR1A 3044/4885
US-20230250118-A1 ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF CRY1, LEF1, PIEZO1 ASIC3 229/4885LOXL2 715/4885HTR1A 2065/4885
US-20150243913-A1 Organic Electroluminescence Device LAGE3, L1CAM, LEF1 ASIC3 1577/4885LOXL2 158/4885HTR1A 4238/4885
US-11832508-B2 Organic electroluminescence device LAGE3, L1CAM, LEF1 ASIC3 1577/4885LOXL2 158/4885HTR1A 4238/4885
US-20120153816-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, LAGE3, LEF1 ASIC3 1698/4885LOXL2 109/4885HTR1A 4137/4885
US-20110049496-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, APOL1, MT-ND4L ASIC3 1769/4885LOXL2 15/4885HTR1A 4669/4885
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 ASIC3 2304/4885LOXL2 71/4885HTR1A 2322/4885
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR ASIC3 1963/4885LOXL2 387/4885HTR1A 2376/4885
US-11744141-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, LBR ASIC3 2045/4885LOXL2 5/4885HTR1A 2207/4885
US-11765966-B2 Organic electroluminescent materials and devices L1CAM, EPCAM, EPM2A ASIC3 413/4885LOXL2 83/4885HTR1A 4520/4885
US-11697662-B2 Organic electroluminescent materials and devices LIFR, C1R, LBR ASIC3 2250/4885LOXL2 436/4885HTR1A 2093/4885
US-11839142-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP ASIC3 2442/4885LOXL2 33/4885HTR1A 2663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.