Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | UGT8 | Q16880 | 3/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790702 | 0.77 | CYP11B2 (0.52) | ALDH1A1KDM4ESMN1; SMN2TDP1CYP11B2 | |
| SCHEMBL10294633 | 0.75 | HTR2A (0.60) | ALDH1A1KDM4EMEN1CYP1A2CYP3A4 | |
| SCHEMBL18791085 | 0.75 | CYP11B2 (0.73) | ALDH1A1KDM4ESMN1; SMN2TDP1CYP11B2 | |
| SCHEMBL18790696 | 0.74 | CYP11B2 (0.61) | CYP11B2UGT8CYP11B1 | |
| SCHEMBL3365732 | 0.73 | HTR2A (0.54) | ALDH1A1KDM4EMEN1CYP1A2CYP3A4 | |
| SCHEMBL23464917 | 0.73 | CHRM5 (0.75) | ALDH1A1KDM4ESMN1; SMN2TDP1MEN1 | |
| SCHEMBL18791083 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2TDP1CYP11B2 | |
| SCHEMBL22236774 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2TDP1CYP11B2 | |
| SCHEMBL12813911 | 0.73 | HTR2A (0.57) | ALDH1A1KDM4EMEN1CYP1A2CYP3A4 | |
| SCHEMBL18790991 | 0.72 | CYP11B2 (0.90) | ALDH1A1KDM4ESMN1; SMN2TDP1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381904-B1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2021-07-28 | — | — | EP | disclosed |
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2020-07-21 | — | — | US | disclosed |
| WO-2017069226-A1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | 田辺三菱製薬株式会社 | 2017-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | REN, NR3C2, NR5A1 | ALDH1A1 1495/4885KDM4E 2819/4885SMN1; SMN2 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.