Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.90 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.42 |
| ▸ | UGT8 | Q16880 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18791082 | 0.84 | CYP11B2 (0.68) | CYP11B2SMN1; SMN2DYRK1AKDM4EALDH1A1 | |
| SCHEMBL18790696 | 0.81 | CYP11B2 (0.61) | CYP11B2PIM2UGT8PIM1CSNK2A2 | |
| SCHEMBL18790698 | 0.77 | CYP11B2 (0.56) | CYP11B2SMN1; SMN2PIM2UGT8PIM1 | |
| SCHEMBL18791085 | 0.76 | CYP11B2 (0.73) | CYP11B2SMN1; SMN2UGT8NOS3NOS1 | |
| SCHEMBL18790990 | 0.72 | ALDH1A1 (0.52) | CYP11B2SMN1; SMN2UGT8KDM4EALDH1A1 | |
| SCHEMBL18790687 | 0.70 | CYP11B2 (0.49) | CYP11B2PIM2PIM1CSNK2A1DYRK1A | |
| SCHEMBL24499935 | 0.68 | PLA2G10 (0.59) | CYP11B2SMN1; SMN2NPC1RAB9ADYRK1A | |
| SCHEMBL18790685 | 0.67 | PIM2 (0.48) | CYP11B2PIM2PIM1CSNK2A2CSNK2A1 | |
| SCHEMBL18790690 | 0.67 | CYP11B2 (0.45) | CYP11B2PIM2PIM1CSNK2A2CSNK2A1 | |
| SCHEMBL18791093 | 0.65 | CYP11B2 (0.66) | CYP11B2SMN1; SMN2KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2020-07-21 | — | — | US | disclosed |
| WO-2017069226-A1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | 田辺三菱製薬株式会社 | 2017-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | REN, NR3C2, NR5A1 | CYP11B2 8/4885SMN1; SMN2 4151/4885NPC1 1279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.