SCHEMBL1887868

SCHEMBL1887868

CCCCc1cc(-c2c(-c3cc(CCCC)c(CC)cc3CCCC)c(-c3cc(CCCC)c(CC)cc3CCCC)c3c(c2-c2cc(CCCC)c(CC)cc2CCCC)=c2ccccc2=3)c(CCCC)cc1CC

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.34
ELANE P08246 2/20 0.33
CTSG P08311 2/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
TYR P14679 1/20 0.33
LIPG Q9Y5X9 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
GPR84 Q9NQS5 1/20 0.30
CTRC Q99895 1/20 0.30
HSP90AA1 P07900 1/20 0.30
MAOA P21397 1/20 0.30
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1893689 0.85 HSP90AA1 (0.32) HSP90AA1
SCHEMBL27771302 0.82 ELANE (0.34) TLR8ELANECTSGNR1H2NR1H3
SCHEMBL5180423 0.79 GPR3 (0.44) TLR8GPR3
SCHEMBL1883533 0.76 ELANE (0.35) ELANECTSGNR1H2NR1H3CTRC
SCHEMBL27747971 0.75 PSMB5 (0.40)
SCHEMBL1879185 0.75 ELANE (0.35) TLR8ELANECTSGTYRLIPG
SCHEMBL674883 0.74 ELANE (0.36) TLR8ELANECTSGNR1H2NR1H3
SCHEMBL27747974 0.74 PSMB5 (0.39) TLR8NR1H2NR1H3
SCHEMBL1885411 0.70 TLR8 (0.36) TLR8TYRLIPGCYP3A4CYP2D6
SCHEMBL27554686 0.70 LIPG (0.43) TLR8NR1H2NR1H3TYRLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-20100104879-A1 CLEAR HARD COAT FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND DISPLAY DEVICE EMPLOYING THE SAME KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed