Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18794843 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBACHEKMT2A | |
| SCHEMBL18794854 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBACHEKMT2A | |
| SCHEMBL2772035 | 0.88 | NPC1 (0.54) | ALDH1A1LMNAPOLBACHEKMT2A | |
| SCHEMBL7981690 | 0.86 | ALDH1A1 (0.58) | ALDH1A1LMNAPOLBACHEKMT2A | |
| SCHEMBL16594980 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAPOLBACHEKMT2A | |
| SCHEMBL18794875 | 0.84 | ALDH1A1 (0.56) | ALDH1A1LMNAPOLBACHEKMT2A | |
| SCHEMBL6096659 | 0.84 | ALDH1A1 (0.56) | ALDH1A1LMNAPOLBACHEKMT2A | |
| SCHEMBL6096663 | 0.84 | ALDH1A1 (0.56) | ALDH1A1LMNAPOLBACHEKMT2A | |
| SCHEMBL1737189 | 0.80 | CTSS (0.47) | ALDH1A1KMT2AMMP2 | |
| SCHEMBL1737187 | 0.80 | CTSS (0.47) | ALDH1A1KMT2AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017070794-A1 | PROCESS FOR THE PREPARATION OF 2-[2-(2-AMINO-2-CARBOXY-ETHYLAMINO)-2-CARBOXY-ETHYLAMINO]-SUCCINIC ACID (AM-A) AND ANALOGS AND DERIVATIVES THEREOF | MCMASTER UNIVERSITY (CA) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017070794-A1 | PROCESS FOR THE PREPARATION OF 2-[2-(2-AMINO-2-CARBOXY-ETHYLAMINO)-2-CARBOXY-ETHYLAMINO]-SUCCINIC ACID (AM-A) AND ANALOGS AND DERIVATIVES THEREOF | MCMASTER UNIVERSITY (CA) | 2017-05-04 | — | — | WO | disclosed |