Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18794861 | 1.00 | ATM (0.49) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL15729475 | 0.94 | ATM (0.54) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL27671960 | 0.84 | TRPM8 (0.50) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL2171165 | 0.84 | TRPM8 (0.50) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL14481880 | 0.84 | MAPT (0.46) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL30988967 | 0.84 | ATM (0.55) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL14481881 | 0.84 | MAPT (0.46) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL15423734 | 0.82 | ITGA4 (0.58) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL304265 | 0.79 | ATM (0.56) | ATMKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL14636601 | 0.79 | ATM (0.56) | ATMKMT2AMEN1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017070794-A1 | PROCESS FOR THE PREPARATION OF 2-[2-(2-AMINO-2-CARBOXY-ETHYLAMINO)-2-CARBOXY-ETHYLAMINO]-SUCCINIC ACID (AM-A) AND ANALOGS AND DERIVATIVES THEREOF | MCMASTER UNIVERSITY (CA) | 2017-05-04 | — | — | WO | disclosed |