Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103227 | 0.89 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1RAB9AGAALMNA | |
| SCHEMBL103228 | 0.89 | SMN1; SMN2 (0.63) | SMN1; SMN2ALDH1A1RAB9AGAALMNA | |
| SCHEMBL3052606 | 0.84 | LMNA (0.65) | SMN1; SMN2ALDH1A1RAB9AGAALMNA | |
| SCHEMBL3052608 | 0.84 | LMNA (0.65) | SMN1; SMN2ALDH1A1RAB9AGAALMNA | |
| SCHEMBL6129052 | 0.79 | PARP10 (0.78) | PTGIRALDH1A1LMNAKMT2AL3MBTL1 | |
| SCHEMBL5788625 | 0.79 | PTGIR (1.00) | PTGIRPRSS1PRSS2PRSS3CA1 | |
| SCHEMBL13153891 | 0.78 | ALDH1A1 (0.50) | ALDH1A1RAB9AGAALMNAKMT2A | |
| SCHEMBL21332333 | 0.78 | ALDH1A1 (0.50) | ALDH1A1RAB9AGAALMNAKMT2A | |
| SCHEMBL482369 | 0.77 | CA1 (0.65) | PTGIRALDH1A1RAB9AGAAKMT2A | |
| Hydrochloric Acid SCHEMBL11848856 | 0.74 | CA1 (0.61) | PTGIRALDH1A1RAB9AGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3367798-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017072247-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-04 | — | — | WO | disclosed |